This post was most recently updated on March 11th, 2022

Best Mouse For Thumb Pain

10 Best Mouse For Thumb Pain 2022 – Reviews & Guide

The best mouse for thumb pain is the Logitech MX Vertical. It has an ergonomic design that won’t aggravate any existing injuries and will reduce the risk of developing Repetitive Strain Injury (RSI).

If you find that using a normal mouse causes you pain, it may be time to switch to an ergonomic mouse designed specifically with your comfort in mind.

The thumb moves in a different way to the rest of your hand. This can put pressure on your wrist and elbow. An ergonomic mouse with vertical thumb support, like the Logitech MX Vertical, will help to alleviate this problem.

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1. Microsoft Sculpt Ergonomic Mouse 

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Brand: Microsoft
  • Series: L6V-00001
  • Color: Black
  • Number of Buttons: 3
  • Item Dimensions LxWxH: 3.87 x 2.23 x 5.51 inches

The Microsoft Sculpt Ergonomic Mouse is a wireless mouse that features an ergonomic design and runs on AA batteries. The mouse connects to your computer wirelessly via Bluetooth, so there’s no need to sync the device with a USB receiver.

If you have wrist pain or discomfort when using the computer, an ergonomic mouse like this one may help. It’s designed to encourage natural hand and wrist postures, thanks to its innovative thumb scoop design. The mouse angle and height are also positioned to support a comfortable wrist position.

The Sculpt Ergonomic Mouse also has four-way scrolling capabilities, so you can easily navigate large spreadsheets or documents. Its Windows button provides instant access to the Start Menu for easy navigation.

2. Logitech M560 Wireless Mouse

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Connectivity Technology: Wireless
  • Brand: Logitech
  • Movement Detection Technology: Optical
  • Color: Black
  • Number of Buttons: 5

I was not impressed with the M560 mouse. I’ve been using the Logitech M510 Wireless Mouse for years. I was looking to replace it because while the shape and feel of the mouse were comfortable, the scroll wheel had given out twice in 3 years and it had recently died again. As a web developer and avid video gamer, I absolutely need a good mouse.

The M560 is NOT a good mouse. For starters, there is no tactile feedback on the scroll wheel and it does not click (it does have a clicky button behind it though). The scroll wheel is designed to have some resistance but this is poorly implemented. It has a rubberized surface and is extremely hard to push or pull in either direction (and as previously mentioned there is no tactile feedback so you can’t tell if you’re actually scrolling or just pushing against an immovable object).

The left/right buttons are not very responsive – they require a bit of force to actuate and do not have “mushy” travel like most mice these days. The left/right buttons under your thumb are even worse – they are very mushy and require a lot of pressure to actuate.

3. Logitech MX Master 2S Wireless Mouse

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Connectivity Technology: Wireless
  • Brand: Logitech
  • Series: 910-005131
  • Special Feature: Alcohol-Free
  • Color: Graphite

The MX Master 2S is the flagship mouse from Logitech, and a new version of the original MX Master. It has several new features including the ability to connect via Bluetooth to three devices simultaneously, which means that you can control your desktop PC, laptop, tablet or smartphone with just one mouse.

The MX Master 2S’s scroll wheel works in two modes: click-to-click for precise navigation (which is helpful when browsing through long documents or web pages) and hyper-fast if you flick it. There’s also a gesture button beneath your thumb which allows you to perform a number of functions including forward/back in web browsers and opening Mission Control on Macs. The mouse supports Logitech’s Flow software, which lets you control multiple computers with one keyboard and mouse; I was easily able to move my cursor between my iMac and MacBook Pro using Flow.

I’ve used a lot of trackpads and mice over the years, but none are as comfortable as the MX Master 2S. I’m not sure what material Logitech uses for the top part of its mice, but they seem to have an almost rubberized feel that helps me grip them better than any other mouse I’ve used.

4. Anker 2.4G Wireless Vertical Ergonomic Optical Mouse

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Connectivity Technology: Wireless
  • Brand: Anker
  • Movement Detection Technology: Optical
  • Color: Black
  • Number of Buttons: 6

I’ve been using the Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for a few months now and I am astounded by how comfortable it is.

This mouse is the most comfortable one I’ve ever used. The position of your hand and wrist with this mouse is natural and feels like you’re using a joystick or game controller. It’s really comfortable and my wrist doesn’t hurt after using it for long periods of time.

The buttons are also very easy to use, unlike some other ergonomic mice which have hard-to-reach side buttons. You can easily find the side buttons by feel alone.

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The usb cord on your computer sticks up (or down, depending on how you have it plugged in) a bit more than other mice, but that shouldn’t be a problem at all.

5. Evoluent VM4RW VerticalMouse 4 Right Hand Ergonomic Mouse

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Brand: Evoluent
  • Series: VM4RW
  • Item model number: 2
  • Hardware Platform: PC
  • Operating System: Linux, Windows XP
  • Item Weight: 8 ounces
  • Product Dimensions: 5.43 x 3 x 4.5 inches
  • Item Dimensions LxWxH: 5.43 x 3 x 4.5 inches

The Evoluent VerticalMouse 4 Right Hand (Regular Size) is an advanced ergonomic mouse that provides superior comfort and ease of use. The unique shape supports your hand in a fully upright handshake position that avoids forearm twisting. Many users, including medical doctors, ergonomists and physical therapists, said the Evoluent VerticalMouse provides superior comfort and even relieved their wrist pain.

The patented new shape supports your right hand in a fully upright handshake position that eliminates forearm twisting. Many users, including medical doctors, ergonomists and physical therapists, said the Evoluent VerticalMouse provides superior comfort and even relieved their wrist pain. The design is not only comfortable but also provides a unique look.

The thumb rest has been reshaped to provide even more comfort over earlier versions. The regular size is for hands measuring up to 3.75 inches from the tip of the middle finger to the crease in the palm.

6. Logitech MX Vertical Wireless Mouse

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Connectivity Technology: Wireless, Bluetooth, USB
  • Brand: Logitech
  • Series: MX Vertical Advanced Ergonomic Mouse
  • Color: Graphite
  • Number of Buttons: 4

The MX Vertical mouse is designed to reduce muscle strain, decrease wrist pressure, and improve posture. It will feel different than a regular mouse at first but give it a chance – your hand will thank you.

Made of high-grade plastic, the MX Vertical has an aluminum plate on the bottom that covers the battery compartment. There are four anti-slip rubber pads on the base, and I really like that Logitech includes a soft cover for the USB receiver.

MX Vertical’s shape is something you have to get used to, but after about a week with it, I started to really appreciate the ergonomics and comfort. The mouse’s height is about 1.5 inches higher than my G703’s and has a 57-degree vertical angle that puts your hand in a handshake position. The top of the mouse has a textured rubber finish that feels smooth and natural in your palm, while the sides of the mouse have soft touch paint with grooves that provide a firm grip when holding or lifting the mouse.

The left side of the MX Vertical houses two thumb buttons which are easily accessible by your thumb without having to twist your palm or wrist. The right side of the mouse has a textured rubber grip which makes picking up or lifting easier if you.

7. Logitech M570 Wireless Trackball Mouse

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Connectivity Technology: Wireless
  • Brand: Logitech
  • Model Name: FBA_LOG910001799
  • Movement Detection Technology: Trackball
  • Color: Dark Gray

The Logitech M570 Wireless Trackball Mouse is designed for comfort and precision. I would recommend this to anyone who likes a trackball mouse. The receiver is small and can be left in your laptop or desktop computer.

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The mouse works great, has a scroll wheel and the receiver can be stored inside the mouse when not in use. It does require 1 AA battery, but it lasts a long time.

I’ve been using this trackball for over a year now at work and its just as good as the first day I started using it. I love it because my hand doesn’t need to move around on my desk while working, which is great because my desk is small. It also doesn’t get dirty like a normal roller ball mouse because you don’t have to lift it up and move it around on the surface you are working on. Plus there are no wires to deal with which is always a plus.

8. Kensington Expert Wireless Trackball Mouse

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Connectivity Technology: Wireless
  • Brand: Kensington
  • Compatible Devices: Laptop, Tablet, Other
  • Series: Expert Mouse
  • Special Feature: Wireless connection via Bluetooth® 4.0 LE or USB nano receiver TrackballWorks™ software lets you customize all 4 buttons, adjust cursor speed wireless connection via Bluetooth® 4.0 LE or USB nano receiver TrackballWorks™ software lets you

This is the best trackball I have ever used. I have been using trackballs for 30+ years and am so happy to see Kensington keeping up with the times and staying true to what has always made them great.

I had been using the old Orbit trackball which is still a great trackball but features no customization options, no middle button, and a smaller ball. However, the new Expert Mouse is much more than just an upgrade to the Orbit. This trackball sports four buttons (not including the scroll ring) and can be customized in many ways. The ball is larger than before at 55mm in diameter and sits in a polished chrome socket that makes it feel more like a race-car steering wheel than a mouse.

The software provided by Kensington allows you to assign custom button commands, adjust scrolling speed, adjust cursor speed, adjust acceleration, trigger button down/up on click, or trigger click on scroll up/down or scroll left/right.

9. Logitech MX Ergo Wireless Trackball Mouse 

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Connectivity Technology: Wireless, Bluetooth, USB
  • Brand: Logitech
  • Series: Logitech MX ERGO
  • Special Feature: Alcohol-Free
  • Movement Detection Technology: Trackball

MX Ergo is the first adjustable performance trackball designed for comfort and control. It’s a new standard of comfort and precision that combines Logitech’s newest trackball innovation with the power of Logitech flow, for the ultimate in cross-computer control.

The trackball works like a mouse, but it stays in one place. You just roll the ball with your thumb, move your cursor, then click. MX Ergo features a unique adjustable hinge for personalized comfort and the latest tracking, scrolling and power management technology.

Two computers are better than one: use MX ergo on your desktop computer and a laptop while you’re on the go; Or connect to up to three devices at once with the included Logitech unifying receiver or via Bluetooth low energy technology.

10. ELECOM 2.4GHz Wireless Finger-operated Large size Trackball Mouse

10 Best Mouse For Thumb Pain 2022 - Reviews & Guide
  • Connectivity Technology: USB
  • Brand: ELECOM
  • Series: M-HT1DRBK
  • Special Feature: Precision Optical Gaming Sensor, 8-Button Function, Finger-operated, 2.4GHz Wireless, Ergonomic DesignPrecision Optical Gaming Sensor, 8-Button Function, Finger-operated, 2.4GHz Wireless, Ergonomic Design 
  • Movement Detection Technology: Optical

A trackball is a pointing device consisting of a ball held by a socket containing sensors to detect rotation of the ball about two axes—like an upside-down mouse with an exposed protruding ball. The user rolls the ball with the thumb, fingers, or the palm of the hand to move a cursor.

Large trackballs are common on CAD workstations for easy precision. Before the advent of the touchpad, small trackballs were common on portable computers, where there may be no desk space on which to run a mouse.

Trackballs are used in applications as varied as computer gaming (especially in first-person shooter video games) and CAD software where fine control is required; in gaming they are also popular for modern action games with first-person perspectives.

Self-contained trackballs come in different sizes and shapes; large trackballs being intended for desktop use, medium ones (about 4 cm diameter) for use with a palm or fingertip and small ones (about 2 cm diameter) for use with the thumb. Some users find them more comfortable than ordinary mice, since only limited wrist movement is required to move the cursor across a large portion of the screen, whereas mice require more arm movement to do so.

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